SEATTLE — Data presented here showed patients with open fractures treated with iodine povacrylex in had similar risks for surgical site infection and unplanned reoperation as those who had a chlorhexidine gluconate solution.
Gerard P. Slobogean MD MPH and his colleagues randomly assigned 22 U.S. hospitals and Canadian hospitals to use an iodine-povacrylex antiseptic or chlorhexidine-gluconate solution for debridement, surgical fixation, and the removal of bone fragments in open fractures (n=1,651 with a mean age of 45 years). During the first two months of recruitment, patients were randomly assigned to either an iodine povacrylex or chlorhexidine gluconate antiseptic solution.
