The American Association of Hip and Knee Surgeons (AAHKS), The American Academy of
Orthopaedic Surgeons (AAOS), The Hip Society, The Knee Society, and The American Society
of Regional Anesthesia and Pain Medicine (ASRA) collaborated to develop evidence-based
guidelines on the use of ketamine in primary total joint arthroplasty (TJA). The purpose
of these guidelines is to improve the treatment of primary TJA patients and reduce
practice variation by promoting a multidisciplinary, evidence-based approach to the
use of ketamine in primary TJA.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select ‘Academic and Personal’
- For corporate R&D use, select ‘Corporate R&D Professionals’
American Academy of Orthoapedic Surgeons (AAOS) AAOS clinical practice guideline and systematic review methodology.
Small-dose ketamine infusion improves postoperative analgesia and rehabilitation after total knee arthroplasty.
Anesth Analg. 2005; 100: 475-480https://doi.org/10.1213/01.ane.0000142117.82241.dc
Pain and recovery after total knee arthroplasty.
Clin J Pain. 2014; 30: 749-754https://doi.org/10.1097/ajp.0000000000000033
Intraoperative low-dose ketamine infusion reduces acute postoperative pain following total knee replacement surgery: a prospective, randomized double-blind placebo-controlled trial.
J Coll Physicians Surg Pak. 2014; 24: 299-303
The analgesic efficiency of combined pregabalin and ketamine for total hip arthroplasty: a randomised, double-blind, controlled study.
Anaesthesia. 2014; 69: 46-52https://doi.org/10.1111/anae.12495
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
Anesth Analg. 2009; 109: 1963-1971https://doi.org/10.1213/ane.0b013e3181bdc8a0
Intraoperative ketamine in total knee arthroplasty does not decrease pain and narcotic consumption: a prospective randomized controlled trial.
J Arthroplasty. 2019; 34: 1640-1645https://doi.org/10.1016/j.arth.2019.04.017
Postoperative analgesia and early rehabilitation after total knee replacement: a comparison of continuous low-dose intravenous ketamine versus nefopam.
Eur J Pain. 2009; 13: 613-619https://doi.org/10.1016/j.ejpain.2008.08.003
Postoperative delirium in total knee and hip arthroplasty patients: a study of perioperative modifiable risk factors.
Br J Anaesth. 2018; 120: 999-1008https://doi.org/10.1016/j.bja.2017.12.046
Risk factors for postoperative delirium in patients undergoing lower extremity joint arthroplasty: a retrospective population-based cohort study.
Reg Anesth Pain Med. 2019; 44: 934https://doi.org/10.1136/rapm-2019-100700
Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial.
Lancet. 2017; 390: 267-275https://doi.org/10.1016/s0140-6736(17)31467-8
One or more of the authors of this paper have disclosed potential or pertinent conflicts of interest, which may include receipt of payment, either direct or indirect, institutional support, or association with an entity in the biomedical field which may be perceived to have potential conflict of interest with this work. For full disclosure statements refer to https://doi.org/10.1016/j.arth.2022.02.122.
© 2022 Elsevier Inc. All rights reserved.
Access this article on ScienceDirect