Annals of the Rheumatic Diseases published data that suggests patients with atopic disease may have an increased risk of developing osteoarthritis.
“We have previously published a study showing that patients with osteoarthritis have increased numbers and activity of mast cells in the joints, which contribute to osteoarthritis pathogenesis,” Matthew C. Baker, MD, of the department of immunology and rheumatology at Stanford University, told Healio. “Mast cells are generally involved in allergic responses, but their mediators (tryptase, histamine) can cause inflammation
