GRAPEVINE, Texas — Melatonin may not improve postoperative sleep disturbance following total knee replacement, according to results presented at the American Association of Hip and Knee Surgeons Annual Meeting.
“Melatonin did not improve subjective sleep quality or patient-reported outcomes at 6 weeks or 90 days following knee replacement,” Drake G. Lebrun, MD, said during his presentation. “We did find that patients who slept poorly tended to fare worse in other realms, as reflected by their worse patient-reported outcomes, and melatonin did not modify any of those
